Negative correlation between maorophage proooagulant and migraion ability in the course of inflammation

The importance of macrophage procoagulant activity (PCA) to cell migration is presumed. In this study we assayed the relationship between the two functions in guinea-pig peritoneal resident macrophages and cells elicited by a sterile inflammation induction, which lasted up to 6 days. The findings pointed to an in vivo induction of PCA in macrophages, which declined with time during inflammation. A clear negative correlation between PCA and random migration ability was demonstrated. Our results suggest that the local induction of coagulation by macrophages may immobilize the cells at the site of inflammation

Precise subtyping for asynchronous multiparty sessions

Session subtyping is a cornerstone of refinement of communicating processes: a process implementing a session type (i.e., a communication protocol) T can be safely used whenever a process implementing one of its supertypes T′ is expected, in any context, without introducing deadlocks nor other communication errors. As a consequence, whenever T T′ holds, it is safe to replace an implementation of T′ with an implementation of the subtype T, which may allow for more optimised communication patterns. We present the first formalisation of the precise subtyping relation for asynchronous multiparty sessions. We show that our subtyping relation is sound (i.e., guarantees safe process replacement, as outlined above) and also complete: any extension of the relation is unsound. To achieve our results, we develop a novel session decomposition technique, from full session types (including internal/external choices) into single input/output session trees (without choices). Previous work studies precise subtyping for binary sessions (with just two participants), or multiparty sessions (with any number of participants) and synchronous interaction. Here, we cover multiparty sessions with asynchronous interaction, where messages are transmitted via FIFO queues (as in the TCP/IP protocol), and prove that our subtyping is both operationally and denotationally precise. In the asynchronous multiparty setting, finding the precise subtyping relation is a highly complex task: this is because, under some conditions, participants can permute the order of their inputs and outputs, by sending some messages earlier or receiving some later, without causing errors; the precise subtyping relation must capture all such valid permutations — and consequently, its formalisation, reasoning and proofs become challenging. Our session decomposition technique overcomes this complexity, expressing the subtyping relation as a composition of refinement relations between single input/output trees, and providing a simple reasoning principle for asynchronous message optimisations

Morphometric Parameters of Erythrocytes in Juvenile Mandarin Ducks Aix galerkulata

The morphometric parameters of erythrocytes in Mandarin ducks Aix galericulata have never been subjected to study even though this species is common in aviculture. The aim of this study is to investigate the morphometric parameters of erythrocytes in juvenile Mandarin ducks. A total of 1500 erythrocytes obtained from thirty Mandarin ducks were analysed. The smears of the peripheral blood were stained using Diff-Quik stain method, and the length and width of erythrocytes were measured using ImageJ program. The average length of the measured erythrocytes was 11.879 mu m. The maximal measured length of the erythrocytes was 10.O49 mu m, and the minimal measured length was 5.668 pm. The average width of the measured erythrocytes vvas 6.160 pm. The maximal measured width of the erythrocytes was 10.115 pm and the minimal measured width vvas 3.750 mu m. In conclusion, knowing morphometric parameters of Mandarin duck erythrocytes is the first step in evaluation process of erythrocytes functional state and health condition of an individual

Decoupling of superconducting layers in magnetic superconductor RuSr_{2}GdCu_{2}O_{8}

We propose the model for magnetic properties of the magnetic superconductor RuSr$_{2}$GdCu$_{2}$O$_{8}$, which incorporates the theory of the superconducting/ferromagnetic multilayers. The transition line $T_{d}(h)$, on which the Josephson coupled superconducting planes are decoupled, i.e. $j_{c}(T_{d})=0$, is calculated as a function of the exchange energy $h$. As the result of this decoupling a nonmonotonic behavior of magnetic properties, like the lower critical field $H_{c1}$, Josephson plasma frequency, etc. is realized near (or by crossing) the $T_{d}(h)$ line. The obtained results are used in analyzing the newly discovered antiferromagnetic ruthenocuprate RuSr$_{2}$GdCu$_{2}$O$_{8}$ with possible weak ferromagnetic order in the RuO planes.Comment: 12 pages, 3 figs embede

Idiopatski i sekundarni stečeni megakolon kod pasa udruženi su sa smanjenom vip-inervacijom u oštećenom kolonu

It is well established that megacolon in carnivores, including both cats and dogs, is a common finding. Megacolon occurs more often in the cat that the dog. Based on current data idiopathic megacolon is a common cause of constipation in cats (62% of constipated cats are affected by diopathic megacolon). There is no evidence of idiopathic megacolon in dogs and publications about this disease in this species is very scarce. We investigated the enteric nervous system in the dilated portion (DP) of the colon in dogs with idiopathic aquired (n=7) or secondary aquired megacolon (n=21) and compared the results with a normal colon in control dogs (n=3). Colonic sections of surgical specimens were investigated by conventional and immunohistochemical methods, including pan-neuronal markers (NSE, synaptophisin, and neurofilament) and VIP, as well as S-100 protein for detection of ganglionic glial cells. Compared to controls, the two megacolon groups showed no changes of density of enteric neurons in both submucosal and myenteric nervous plexuses in DP of the colon and of enteric glial cells. However, compared to controls and dogs with secondary megacolon, there was a significant decrease in the density of NFP-ir nerve fibers in the longitudinal muscle layer in dogs with idiopathic acquired megacolon. In addition, dogs with idiopathic megacolon display decreased VIP-ir in the myenteric plexus and lamina propria mucosae, and absence of VIP-ir neurons in the submucosal plexus of DP of the colon. Similar alterations, although of lesser severity, may be found in dogs with secondary aquired megacolon. We consider that both idiopathic and secondary aquired megacolon might occur on the basis of a dysplastic changes of VIP-ir enteric neurons.Poznato je da se magakolon javlja kod mesojeda, uključujući mačke i pse, pri čemu je ovo oboljenje daleko učestalije kod mačaka. Na osnovu dosadašnjih saznanja, idiopatski megakolon je čest uzročnik konstipacije kod mačaka i 62% mačaka sa konstipacijom ima idiopatski megakolon. Istovremeno, podaci o psima sa idiopatskim megakolonom veoma su oskudni. U ovom radu je proučavan enterični nervni sistem u dilatiranom delu kolona kod 7 pasa sa idiopatskim megakolonom i 21 psa sa sekundarnim stečenim megakolonom, a rezultati su upoređeni sa normalnim kolonom kod 3 kontrolne zdrave životinje. Tkivni preseci kolona bojeni su klasičnim histološkim i imunohistohemijskim metodama, pri čemu su primenjeni pan-neuronski markeri (NSE, sinaptofizin i neurofilament) i VIP, kao i S-100 protein za detekciju glijalnih ćelija u enteričnim ganglijama. Nisu otkrivene razlike u gustini enteričnih neurona u submukoznom i mijenteričnom pleksusu kod životinja sa megakolonom, kao ni razlike u gustini glijalnih ćelija enteričnih ganglija, u odnosu na kontrolnu grupu životinja. Međutim, u odnosu na kontrolnu grupu, kod životinja sa idiopatskim megakolonom dokazana je smanjena VIP-imunoreaktivnost (ir) u mienteričnom pleksusu i krznu mukoze, kao i kompletno odsustvo VIP-ir neurona u submukoznom pleksusu dilatiranog dela kolona. Slične promene, ali u manjem stepenu, postojale su kod pasa sa sekundarnim stečenim megakolonom. Može da se zaključi da u patogenezi idiopatskog i sekundarnog stečenog megakolona značajnu ulogu imaju displastične promene u VIP-ergičkim neuronima enteričkog nervnog sistema

Antioxidant Response in Gills of Eurasian Perch ( Perca fluviatilis ) to Cyanobacterial Bloom Exposure in the Gruža Reservoir

The aim of this study was to assess the impact of an Aphanizomenon flos-aquae bloom in the Gruža Reservoir on the antioxidant parameters measured in the gill cells of Eurasian perch (Perca fluviatilis). Effects of the bloom were evaluated through copper, zinc and manganese containing superoxide dismutase (CuZnSOD and MnSOD), catalase (CAT), glutathione peroxidase (GSH-Px), glutathione reductase (GR) and biotransformation phase II enzyme glutathione-S-transferase (GST) activities and glutathione (GSH) and sulfydryl (–SH) groups concentrations. The activities of CuZn SOD and Mn SOD decreased during the cyanobacterial bloom compared to the period before the bloom. The opposite trend was observed for CAT and GSH-Px activities that increased. During the bloom GR and GST activities and GSH concentration decreased significantly. CuZn SOD, GR and GST activities are detected as the most important parameters for individual variations. Our results indicated that an A. flos-aquae bloom promotes oxidative stress in the gills of P. fluviatilis. The investigated parameters could be used in environmental risk assessment procedures to monitor the effects of A. flos-aquae blooms on fish. Observed changes in the antioxidant parameters in P. fluviatilis gills make them potential biomarkers in the research of ecological risk situations in freshwater ecosystems with frequent cyanobacterial blooms.Water Research and Management (2016), 6(2): 19-2

Estimates of weldability and selection of the optimal procedure and technology for welding of high strength steels

High strength steels belong into a group of high quality steels, with exceptional mechanical properties, especially in regards to tensile strength. At the same time, as their deficiency is emphasized the limited and difficult weldability. In other words, some of those steels are weldable only with application of special measures related to controlled heat input. In that way, the favorable mechanical properties can be kept within the heat affected zone, with condition that the optimal welding technology is selected. Existing, very scarce and often unclear and insufficient recommendations for selection of the optimal welding technology are one of the causes of large number of flaws in welded joints. Mentioned problems, as well as others, can be successfully solved by proper selection of the procedure, filler metal and technology of welding, verified by experiments conducted in laboratory or in real operating conditions. Those experiments can not be performed in arbitrary conditions. Thus, partially due to results reported in this paper, technologists will obtain the possibility to predict in advance, in a very short time period, the mechanical and metallurgical properties of joints of this class of high strength steels. This will be possible without conducting the large number of practical tests or relying on personal experience of a designer

Microwave-induced pi-junction transition in a superconductor / quantum-dot / superconductor structure

Using the nonequilibrium Green function, we show that microwave irradiation can reverse the supercurrent flowing through a superconductor / quantum-dot / superconductor structure. In contrast with the conventional sideband effect in normal-metal / quantum-dot / normal-metal junctions, the photon-assisted structures appear near $E_{0}=\frac{n}{2}\hbar \omega (n=\pm 1,\pm 2...)$, where $E_{0}$ is the resonant energy level of the quantum dot and $\omega$ is the frequency of microwave field. Each photon-assisted structure is composed of a negative and a positive peak, with an abrupt jump from the negative peak to the positive peak around $E_{0}=\frac{n}{2}\hbar \omega$. The microwave-induced $\pi$-junction transition is interpreted in the picture of photon-assisted Andreev bound states, which are formed due to multiple photon-assisted Andreev reflection between the two superconductors. Moreover, the main resonance located at $E_{0}=0$ can also be reversed with proper microwave strength and frequency.Comment: 10 pagres, 3 figure

Supplementary data for the article: Borković-Mitić, S. S.; Prokić, M. D.; Krizmanić, I. I.; Mutić, J.; Trifković, J.; Gavrić, J.; Despotović, S. G.; Gavrilović, B. R.; Radovanović, T. B.; Pavlović, S. Z.; et al. Biomarkers of Oxidative Stress and Metal Accumulation in Marsh Frog (Pelophylax Ridibundus). Environmental Science and Pollution Research 2016, 23 (10), 9649–9659. https://doi.org/10.1007/s11356-016-6194-3

Supplementary material for: [https://doi.org/10.1007/s11356-016-6194-3]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/1941

Supplementary data for the article: Prokić, M. D.; Borković-Mitić, S. S.; Krizmanić, I. I.; Mutić, J. J.; Trifković, J. Đ.; Gavrić, J. P.; Despotović, S. G.; Gavrilović, B. R.; Radovanović, T. B.; Pavlović, S. Z.; et al. Bioaccumulation and Effects of Metals on Oxidative Stress and Neurotoxicity Parameters in the Frogs from the Pelophylax Esculentus Complex. Ecotoxicology 2016, 25 (8), 1531–1542. https://doi.org/10.1007/s10646-016-1707-x

Supplementary material for: [https://doi.org/10.1007/s10646-016-1707-x]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789/2340